Chief physician, Professor, Doctoral Tutor, Deputy Dean of Qilu Hospital, Shandong University，Dean of Qilu Hospital, Shandong University (Qingdao), Director of Brain Center, specially appointed Expert of Taishan Scholar. The main research direction is the diagnosis and treatment of neuromuscular diseases, neurogenetic metabolic diseases and rare diseases of the nervous system, especially in genetically degenerative diseases of the nervous system, muscle weakness, muscular atrophy, peripheral nerve diseases and neuroimmune diseases. He found that vitamin B2 alone has a positive effect on lipid deposit myopathy for the first time, and the research results have benefited hundreds of patients with lipid deposit myopathy. In the study of clinical and pathological mechanisms of mitochondrial disease, glycogen accumulation disease and inflammatory myopathy, remarkable research results have also been obtained. He has published more than 100 papers, including SCI papers as the first or corresponding author in international journals such as "Lancet", "Annals of Neurology", "Neurology", "Acta Neuropathologica", "J Neurol Neurosurg Psychiatry" and "Stroke".